| Gene Information | |
|---|---|
| Gene Name | EPSTI1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 318 |
| Protein Names | Epithelial-stromal interaction protein 1 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000133106 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q96J88 |
| Gene Card | EPSTI1 |
| Uniprot ID | Q96J88 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.028144369) |
| Ortholog in Animals | Alpaca_ EPSTI1 ( ortholog_one2one ) Macaque_ EPSTI1 ( ortholog_one2one ) Mouse_ Epsti1 ( ortholog_one2one ) Pig_ EPSTI1 ( ortholog_one2one ) Rat_ Epsti1 ( ortholog_one2one ) Rabbit_ EPSTI1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in placenta, small intestine, spleen, kidney, thymus, liver, salivary gland and testes. Weakly expressed in breast, skeletal muscle and colon. Highly expressed in breast cancer upon interaction between tumor cells and stromal cells in vitro. Expressed in blood mononuclear cells from patients with systemic lupus erythematosus (SLE). {ECO:0000269|PubMed:11991720, ECO:0000269|PubMed:16769699}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11557739 rs1044856 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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