Gene Information
Gene NameEPS8L3
OrganismHomo sapiens (Human)
Gene Length593
Protein NamesEpidermal growth factor receptor kinase substrate 8-like protein 3 (EPS8-like protein 3) (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-related protein 3)
Target NameNA
Target TypeNA
Gene Age987 ( ENSG00000198758 )
Evolutionary StageEumetazoa
AlphaFoldDBQ8TE67
Gene CardEPS8L3
Uniprot IDQ8TE67
PfamPF08416; PF18016; PF00018
In ASDno
Allosteric Predictionno (-1.115583421)
Ortholog in AnimalsAlpaca_ EPS8L3 ( ortholog_one2one )
Dog_ EPS8L3 ( ortholog_one2one )
Macaque_ EPS8L3 ( ortholog_one2one )
Mouse_ Eps8l3 ( ortholog_one2one )
Pig_ EPS8L3 ( ortholog_one2one )
Rat_ Eps8l3 ( ortholog_one2one )
Rabbit_ EPS8L3 ( ortholog_one2one )
OhnologsEPS8, EPS8L2
ParalogsEPS8L2, EPS8, EPS8L1
Tissuecolon, duodenum, rectum, small.intestine, stomach, gall.bladder, small.intestine.Peyers.patch, transverse.colon
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1WXT  (NMR 
DBSNP rs17598321  rs6693815  rs3818562  rs11102001  rs35072794 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:14565974}.
Mouse PG classificationNA
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