| Gene Information | |
|---|---|
| Gene Name | EMC1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 993 |
| Protein Names | ER membrane protein complex subunit 1 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000127463 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8N766 |
| Gene Card | EMC1 |
| Uniprot ID | Q8N766 |
| Pfam | PF07774; PF13360 |
| In ASD | no |
| Allosteric Prediction | no (-1.032829357) |
| Ortholog in Animals | Alpaca_ EMC1 ( ortholog_one2one ) Dog_ EMC1 ( ortholog_one2one ) GuineaPig_ EMC1 ( ortholog_one2one ) Macaque_ EMC1 ( ortholog_one2one ) Mouse_ Emc1 ( ortholog_one2one ) Pig_ EMC1 ( ortholog_one2one ) Rat_ Emc1 ( ortholog_one2one ) Rabbit_ EMC1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.038039(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6WW7 (EM 3.40A ) 6Z3W (EM 6.40A ) 7ADO (EM 3.39A ) 7ADP (EM 3.60A ) |
| DBSNP | rs869320625 rs869320623 rs3850531 rs709683 rs709682 rs879253819 rs869320626 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:22119785}; Single-pass type I membrane protein {ECO:0000269|PubMed:32439656, ECO:0000269|PubMed:32459176}. |
| Mouse PG classification | NA |
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