| Gene Information | |
|---|---|
| Gene Name | ITIH5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 942 |
| Protein Names | Inter-alpha-trypsin inhibitor heavy chain H5 (ITI heavy chain H5) (ITI-HC5) (Inter-alpha-inhibitor heavy chain 5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000123243 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q86UX2 |
| Gene Card | ITIH5 |
| Uniprot ID | Q86UX2 |
| Pfam | PF06668; PF08487; PF00092 |
| In ASD | no |
| Allosteric Prediction | no (-0.952156074) |
| Ortholog in Animals | Alpaca_ ITIH5 ( ortholog_one2one ) Dog_ ITIH5 ( ortholog_one2one ) GuineaPig_ ITIH5 ( ortholog_one2one ) Macaque_ ITIH5 ( ortholog_one2one ) Mouse_ Itih5 ( ortholog_one2one ) Pig_ ITIH5 ( ortholog_one2one ) Rat_ AABR07028488.1 ( ortholog_one2one ) Rabbit_ ITIH5 ( ortholog_one2one ) |
| Ohnologs | ITIH6, ITIH4, ITIH1, ITIH3 |
| Paralogs | VWA5A, ITIH4, VWA5B2, ITIH3, VWA5B1, ITIH2, VWA3B, PARP4, ITIH6, ITIH1, VWA3A |
| Tissue | NA |
| Tissue Specificity | Abundantly expressed in placenta. Less abundant expression in mammary gland and ovary. Expression is barely detectable levels in all other tissues tested. {ECO:0000269|PubMed:14744536}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12761771 rs36056263 rs36056263 rs35892621 rs2275069 rs34213756 rs10795551 |
| Subcellular location [CC] | Secreted {ECO:0000250}. |
| Mouse PG classification | NA |
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