| Gene Information | |
|---|---|
| Gene Name | EPO |
| Organism | Homo sapiens (Human) |
| Gene Length | 193 |
| Protein Names | Erythropoietin (Epoetin) |
| Target Name | erythropoietin |
| Target Type | Clinical trial target |
| Gene Age | 645 ( ENSG00000130427 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P01588 |
| Gene Card | EPO |
| Uniprot ID | P01588 |
| Pfam | PF00758 |
| In ASD | no |
| Allosteric Prediction | yes (0.764838522) |
| Ortholog in Animals | Alpaca_ EPO ( ortholog_one2many ) Dog_ epo ( ortholog_one2one ) GuineaPig_ EPO ( ortholog_one2one ) Macaque_ EPO ( ortholog_one2one ) Mouse_ Epo ( ortholog_one2one ) Pig_ EPO ( ortholog_one2one ) Rat_ Epo ( ortholog_one2one ) Rabbit_ EPO ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Produced by kidney or liver of adult mammals and by liver of fetal or neonatal mammals. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.004323(Rat);0.066667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1BUY (NMR - ) 1CN4 (X-ray 2.80A ) 1EER (X-ray 1.90A ) |
| DBSNP | rs62483572 rs137953994 rs11976235 rs149431976 rs1358275550 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:32989016}. |
| Mouse PG classification | NA |
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