| Gene Information | |
|---|---|
| Gene Name | EPIPL |
| Organism | Homo sapiens (Human) |
| Gene Length | 5088 |
| Protein Names | Epiplakin (450 kDa epidermal antigen) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | NA |
| Gene Card | EPPK1 |
| Uniprot ID | P58107 |
| Pfam | PF00681 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in epithelial cells of liver, small intestine, colon, salivary glands, stomach and appendix. {ECO:0000269|PubMed:11278896}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cytoskeleton {ECO:0000269|PubMed:15671067, ECO:0000269|PubMed:23398049}. Cell junction, hemidesmosome {ECO:0000269|PubMed:23398049}. Cell junction, tight junction {ECO:0000269|PubMed:23398049}. Cell projection {ECO:0000269|PubMed:23398049}. Apicolateral cell membrane {ECO:0000250|UniProtKB:Q8R0W0}. Basolateral cell membrane {ECO:0000250|UniProtKB:Q8R0W0}. Cell junction {ECO:0000250|UniProtKB:Q8R0W0}. Note=May move dynamically from bundling intermediate filaments in the cytoplasm or at the cell periphery and reinforcing them (PubMed:23398049). Decorates the keratin intermediate filaments (IF) network and partially that of vimentin (PubMed:15671067). {ECO:0000269|PubMed:15671067, ECO:0000269|PubMed:23398049}. |
| Mouse PG classification | NA |
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