| Gene Information | |
|---|---|
| Gene Name | EPHX1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 455 |
| Protein Names | Epoxide hydrolase 1 (EC 3.3.2.9) (Epoxide hydratase) (Microsomal epoxide hydrolase) (mEH) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000143819 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P07099 |
| Gene Card | EPHX1 |
| Uniprot ID | P07099 |
| Pfam | PF00561 |
| In ASD | no |
| Allosteric Prediction | yes (0.062984873) |
| Ortholog in Animals | Alpaca_ EPHX1 ( ortholog_one2one ) Dog_ EPHX1 ( ortholog_one2one ) GuineaPig_ EPHX1 ( ortholog_one2one ) Macaque_ EPHX1 ( ortholog_one2one ) Mouse_ Ephx1 ( ortholog_one2one ) Pig_ EPHX1 ( ortholog_one2one ) Rat_ Ephx1 ( ortholog_one2one ) Rabbit_ EPHX1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Found in liver. {ECO:0000269|PubMed:12878321}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3738046 rs745306359 rs2234697 rs1051740 rs2234922 rs35073925 rs45449793 rs45495897 rs45563137 rs2234701 |
| Subcellular location [CC] | Microsome membrane {ECO:0000269|PubMed:24958911}; Single-pass type III membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P07687}; Single-pass type III membrane protein {ECO:0000250|UniProtKB:P07687}. |
| Mouse PG classification | NA |
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