| Gene Information | |
|---|---|
| Gene Name | LDHD |
| Organism | Homo sapiens (Human) |
| Gene Length | 507 |
| Protein Names | Probable D-lactate dehydrogenase, mitochondrial (DLD) (Lactate dehydrogenase D) (EC 1.1.2.4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000166816 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q86WU2 |
| Gene Card | LDHD |
| Uniprot ID | Q86WU2 |
| Pfam | PF02913; PF01565 |
| In ASD | no |
| Allosteric Prediction | no (-0.500481628) |
| Ortholog in Animals | Alpaca_ LDHD ( ortholog_one2one ) Dog_ LDHD ( ortholog_one2one ) GuineaPig_ LDHD ( ortholog_one2one ) Macaque_ LDHD ( ortholog_one2one ) Mouse_ Ldhd ( ortholog_one2one ) Pig_ LDHD ( ortholog_one2one ) Rat_ Ldhd ( ortholog_one2one ) Rabbit_ LDHD ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | AGPS, D2HGDH |
| Tissue | NA |
| Tissue Specificity | Expressed moderately in heart and liver and at lower levels in skeletal muscle and kidney. {ECO:0000269|PubMed:12127981}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.2(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11644820 rs1567502487 rs764877688 |
| Subcellular location [CC] | Mitochondrion {ECO:0000250|UniProtKB:Q7TNG8}. |
| Mouse PG classification | NA |
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