| Gene Information | |
|---|---|
| Gene Name | NCAM2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 837 |
| Protein Names | Neural cell adhesion molecule 2 (N-CAM-2) (NCAM-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000154654 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O15394 |
| Gene Card | NCAM2 |
| Uniprot ID | O15394 |
| Pfam | PF00041; PF07679 |
| In ASD | no |
| Allosteric Prediction | no (-0.96843998) |
| Ortholog in Animals | Alpaca_ NCAM2 ( ortholog_one2one ) Dog_ NCAM2 ( ortholog_one2one ) GuineaPig_ NCAM2 ( ortholog_one2one ) Macaque_ NCAM2 ( ortholog_one2one ) Mouse_ Ncam2 ( ortholog_one2one ) Pig_ NCAM2 ( ortholog_one2one ) Rat_ Ncam2 ( ortholog_one2one ) Rabbit_ NCAM2 ( ortholog_one2one ) |
| Ohnologs | NCAM1 |
| Paralogs | CNTN5, CNTN2, NFASC, ROBO2, SDK1, SDK2, CNTN3, HMCN2, CNTN6, DSCAML1, VSIG10L, CNTN1, IGDCC4, IGSF21, VCAM1, ROBO1, L1CAM, BOC, DCC, IGDCC3, ROBO4, IGSF9, VSIG10, DSCAM, CDON, NCAM1, ROBO3, CHL1, NRCAM, NEO1, IGSF9B, MXRA5, IGSF10, PTPRQ, PRTG, CNTN4 |
| Tissue | cerebral.cortex |
| Tissue Specificity | Expressed most strongly in adult and fetal brain. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.350650(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2DOC (NMR - ) 2JLL (X-ray 2.30A ) 2KBG (NMR - ) 2V5T (X-ray 2.00A ) 2VAJ (X-ray 2.70A ) 2WIM (X-ray 3.00A ) 2XY1 (X-ray 1.90A ) 2XY2 (X-ray 1.77A ) 2XYC (X-ray 2.65A ) |
| DBSNP | rs35654962 rs232518 |
| Subcellular location [CC] | Cell membrane; Single-pass type I membrane protein. |
| Mouse PG classification | NA |
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