| Gene Information | |
|---|---|
| Gene Name | EPCR |
| Organism | Homo sapiens (Human) |
| Gene Length | 238 |
| Protein Names | Endothelial protein C receptor (Activated protein C receptor) (APC receptor) (Endothelial cell protein C receptor) (CD antigen CD201) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9UNN8 |
| Gene Card | PROCR |
| Uniprot ID | Q9UNN8 |
| Pfam | PF16497 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed strongly in the endothelial cells of arteries and veins in heart and lung, less intensely in capillaries in the lung and skin, and not at all in the endothelium of small vessels of the liver and kidney. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);0.004323(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1L8J (X-ray 2.00A ) 1LQV (X-ray 1.60A ) 3JTC (X-ray 1.60A ) 4V3D (X-ray 2.65A ) 4V3E (X-ray 2.90A ) 6SNY (X-ray 3.11A ) 7OKS (X-ray 1.95A ) 7OKT (X-ray 1.95A ) 7OKU (X-ray 1.95A ) 7OKV (X-ray 1.85A ) |
| DBSNP | rs867186 |
| Subcellular location [CC] | Membrane; Single-pass type I membrane protein. |
| Mouse PG classification | NA |
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