Gene Information | |
---|---|
Gene Name | EPB41L4B |
Organism | Homo sapiens (Human) |
Gene Length | 900 |
Protein Names | Band 4.1-like protein 4B (Erythrocyte membrane protein band 4.1-like 4B) (FERM-containing protein CG1) (Protein EHM2) |
Target Name | NA |
Target Type | NA |
Gene Age | 987 ( ENSG00000095203 ) |
Evolutionary Stage | Opisthokonta |
AlphaFoldDB | Q9H329 |
Gene Card | EPB41L4B |
Uniprot ID | Q9H329 |
Pfam | PF08736; PF09380; PF00373; PF09379 |
In ASD | no |
Allosteric Prediction | no (-0.178060502) |
Ortholog in Animals | Alpaca_ EPB41L4B ( ortholog_one2one ) Dog_ EPB41L4B ( ortholog_one2one ) GuineaPig_ EPB41L4B ( ortholog_one2one ) Macaque_ EPB41L4B ( ortholog_one2one ) Mouse_ Epb41l4b ( ortholog_one2one ) Pig_ EPB41L4B ( ortholog_one2one ) Rat_ Epb41l4b ( ortholog_one2one ) Rabbit_ EPB41L4B ( ortholog_one2one ) |
Ohnologs | EPB41L5 |
Paralogs | EPB41L2, FRMD3, EPB41, EPB41L5, FRMD6, FRMD5, EPB41L4A, MYLIP, EPB41L3, EPB41L1 |
Tissue | pancreas |
Tissue Specificity | Expressed at higher levels in acute wounds than chronic wounds with increased expression in healing wounds, especially at the leading wound edge (PubMed:23664528). Isoform 1 is highly expressed in brain. Isoform 2 is highly expressed in testis with lower levels in prostate and breast (PubMed:14521927). {ECO:0000269|PubMed:14521927, ECO:0000269|PubMed:23664528}. |
Pharmacological Animal Models | NA |
Gene Ontology (biological process) |
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Gene Ontology (cellular component) |
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Gene Ontology (molecular function) |
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PDB | NA |
DBSNP | rs3750450 |
Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:22006950}. Cell junction, tight junction {ECO:0000269|PubMed:22006950}. Note=Accumulates along apical cell-cell boundaries and is also detected in the cytoplasm in a punctate manner. {ECO:0000269|PubMed:22006950}. |
Mouse PG classification | NA |
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