Gene Information
Gene NameEPB41L2
OrganismHomo sapiens (Human)
Gene Length1005
Protein NamesBand 4.1-like protein 2 (Erythrocyte membrane protein band 4.1-like 2) (Generally expressed protein 4.1) (4.1G)
Target NameNA
Target TypeNA
Gene Age810 ( ENSG00000079819 )
Evolutionary StageOpisthokonta
AlphaFoldDBO43491
Gene CardEPB41L2
Uniprot IDO43491
PfamPF05902; PF08736; PF09380; PF00373; PF09379; PF04382
In ASDno
Allosteric Predictionyes (0.488813107)
Ortholog in AnimalsAlpaca_ EPB41L2 ( ortholog_one2one )
Dog_ EPB41L2 ( ortholog_one2one )
GuineaPig_ EPB41L2 ( ortholog_one2one )
Macaque_ EPB41L2 ( ortholog_one2one )
Mouse_ Epb41l2 ( ortholog_one2one )
Pig_ EPB41L2 ( ortholog_one2one )
Rat_ Epb41l2 ( ortholog_one2one )
Rabbit_ EPB41L2 ( ortholog_one2one )
OhnologsEPB41L3, EPB41
ParalogsFRMD3, EPB41, EPB41L5, FRMD6, FRMD5, EPB41L4B, EPB41L4A, MYLIP, EPB41L3, EPB41L1
TissueNA
Tissue SpecificityWidely expressed.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs2297852 
Subcellular location [CC]Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm, cell cortex {ECO:0000269|PubMed:23870127}. Cell membrane {ECO:0000269|PubMed:22361696}.
Mouse PG classificationNA
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