| Gene Information | |
|---|---|
| Gene Name | EPB41 |
| Organism | Homo sapiens (Human) |
| Gene Length | 864 |
| Protein Names | Protein 4.1 (P4.1) (4.1R) (Band 4.1) (EPB4.1) (Erythrocyte membrane protein band 4.1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000159023 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | P11171 |
| Gene Card | EPB41 |
| Uniprot ID | P11171 |
| Pfam | PF05902; PF08736; PF09380; PF00373; PF09379; PF04382 |
| In ASD | no |
| Allosteric Prediction | yes (0.441897442) |
| Ortholog in Animals | Alpaca_ EPB41 ( ortholog_one2one ) Dog_ EPB41 ( ortholog_one2one ) GuineaPig_ EPB41 ( ortholog_one2one ) Macaque_ EPB41 ( ortholog_one2one ) Mouse_ Epb41 ( ortholog_one2one ) Pig_ EPB41 ( ortholog_one2one ) Rat_ Epb41 ( ortholog_one2one ) Rabbit_ EPB41 ( ortholog_one2one ) |
| Ohnologs | EPB41L2, EPB41L3 |
| Paralogs | EPB41L2, FRMD3, EPB41L5, FRMD6, FRMD5, EPB41L4B, EPB41L4A, MYLIP, EPB41L3, EPB41L1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1GG3 (X-ray 2.80A ) 2RQ1 (NMR - ) 3QIJ (X-ray 1.80A ) |
| DBSNP | rs111642750 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton {ECO:0000269|PubMed:12427749}. Cytoplasm, cell cortex {ECO:0000269|PubMed:12427749, ECO:0000269|PubMed:23870127}. Nucleus {ECO:0000269|PubMed:12427749}. |
| Mouse PG classification | HPG |
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