| Gene Information | |
|---|---|
| Gene Name | EPAC2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1011 |
| Protein Names | Rap guanine nucleotide exchange factor 4 (Exchange factor directly activated by cAMP 2) (Exchange protein directly activated by cAMP 2) (EPAC 2) (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q8WZA2 |
| Gene Card | RAPGEF4 |
| Uniprot ID | Q8WZA2 |
| Pfam | PF00027; PF00610; PF00617; PF00618 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Predominantly expressed in brain and adrenal gland. Isoform 2 is expressed in liver. Isoform 1 is expressed in liver at very low levels. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. |
| Mouse PG classification | NA |
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