| Gene Information | |
|---|---|
| Gene Name | EPAC |
| Organism | Homo sapiens (Human) |
| Gene Length | 923 |
| Protein Names | Rap guanine nucleotide exchange factor 3 (Exchange factor directly activated by cAMP 1) (Exchange protein directly activated by cAMP 1) (EPAC 1) (Rap1 guanine-nucleotide-exchange factor directly activated by cAMP) (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O95398 |
| Gene Card | RAPGEF3 |
| Uniprot ID | O95398 |
| Pfam | PF00027; PF00610; PF00617; PF00618 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed with highest levels in adult kidney, heart, thyroid and brain, and fetal kidney. {ECO:0000269|PubMed:9856955}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6H7E (X-ray 2.30A ) |
| DBSNP | rs11168230 rs2016123 rs12422983 rs61709815 |
| Subcellular location [CC] | Endomembrane system {ECO:0000269|PubMed:10777494}. |
| Mouse PG classification | NA |
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