| Gene Information | |
|---|---|
| Gene Name | ENTPD6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 484 |
| Protein Names | Ectonucleoside triphosphate diphosphohydrolase 6 (NTPDase 6) (EC 3.6.1.6) (CD39 antigen-like 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000197586 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O75354 |
| Gene Card | ENTPD6 |
| Uniprot ID | O75354 |
| Pfam | PF01150 |
| In ASD | no |
| Allosteric Prediction | yes (0.6474293) |
| Ortholog in Animals | Alpaca_ ENTPD6 ( ortholog_one2one ) Dog_ ENTPD6 ( ortholog_one2one ) GuineaPig_ ENTPD6 ( ortholog_one2one ) Mouse_ Entpd6 ( ortholog_one2one ) Pig_ ENTPD6 ( ortholog_one2one ) Rat_ Entpd6 ( ortholog_one2one ) Rabbit_ ENTPD6 ( ortholog_one2one ) |
| Ohnologs | ENTPD5 |
| Paralogs | ENTPD5, ENTPD8, ENTPD1, ENTPD3, ENTPD2, ENTPD4, ENTPD7 |
| Tissue | NA |
| Tissue Specificity | Expressed in most tissues, but predominantly in heart. {ECO:0000269|PubMed:11041856}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs2076559 rs1044567 rs34007133 rs6050446 rs6138541 |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000250|UniProtKB:Q9ER31}; Single-pass type II membrane protein {ECO:0000255}. Secreted {ECO:0000269|PubMed:10948193, ECO:0000269|PubMed:11041856}. Cell membrane {ECO:0000269|PubMed:10948193, ECO:0000269|PubMed:11041856}; Single-pass type II membrane protein {ECO:0000255}. Note=Exists as a secreted and membrane-bound forms in the medium of transfected cells, the secreted form is predominant. {ECO:0000269|PubMed:10948193, ECO:0000269|PubMed:11041856}. |
| Mouse PG classification | NA |
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