Gene Information
Gene NameENTPD5
OrganismHomo sapiens (Human)
Gene Length428
Protein NamesNucleoside diphosphate phosphatase ENTPD5 (EC 3.6.1.6) (CD39 antigen-like 4) (ER-UDPase) (Ectonucleoside triphosphate diphosphohydrolase 5) (NTPDase 5) (Guanosine-diphosphatase ENTPD5) (GDPase ENTPD5) (Inosine diphosphate phosphatase ENTPD5) (Nucleoside diphosphatase) (Uridine-diphosphatase ENTPD5) (UDPase ENTPD5)
Target NameNA
Target TypeNA
Gene Age950 ( ENSG00000187097 )
Evolutionary StageEukaryota
AlphaFoldDBO75356
Gene CardENTPD5
Uniprot IDO75356
PfamPF01150
In ASDno
Allosteric Predictionyes (0.330410153)
Ortholog in AnimalsAlpaca_ ENTPD5 ( ortholog_one2one )
Dog_ ENTPD5 ( ortholog_one2one )
GuineaPig_ ENTPD5 ( ortholog_one2one )
Mouse_ Entpd5 ( ortholog_one2one )
Pig_ ENTPD5 ( ortholog_one2one )
Rat_ Entpd5 ( ortholog_one2one )
OhnologsENTPD6
ParalogsENTPD6, ENTPD8, ENTPD1, ENTPD3, ENTPD2, ENTPD4, ENTPD7
TissueNA
Tissue SpecificityExpressed in adult liver, kidney, prostate, testis and colon. Much weaker expression in other tissues. {ECO:0000269|PubMed:9676430}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs17094434 
Subcellular location [CC]Endoplasmic reticulum {ECO:0000250|UniProtKB:Q9WUZ9}. Secreted {ECO:0000269|PubMed:10400613, ECO:0000269|PubMed:15698960}.
Mouse PG classificationNA
click here to return to the previous page