| Gene Information | |
|---|---|
| Gene Name | TAAR1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 339 |
| Protein Names | Trace amine-associated receptor 1 (TaR-1) (Trace amine receptor 1) |
| Target Name | trace amine-associated receptor 1 |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000146399 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q96RJ0 |
| Gene Card | TAAR1 |
| Uniprot ID | Q96RJ0 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | yes (1.299807342) |
| Ortholog in Animals | Alpaca_ TAAR1 ( ortholog_one2one ) GuineaPig_ TAAR1 ( ortholog_one2one ) Macaque_ TAAR1 ( ortholog_one2one ) Mouse_ Taar1 ( ortholog_one2one ) Rat_ Taar1 ( ortholog_one2one ) Rabbit_ TAAR1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | HRH2, TAAR6, DRD4, HRH1, DRD1, GPR52, HTR1A, HTR1D, CHRM3, CHRM4, HRH3, TAAR5, HTR4, GPR21, CHRM1, HRH4, TAAR9, CHRM5, TAAR8, DRD3, GPR84, CHRM2, GPR161, DRD5, TAAR2 |
| Tissue | NA |
| Tissue Specificity | Detected in low levels in discrete regions within the central nervous system and in several peripheral tissues. Moderately expressed in stomach. Low levels in amygdala, kidney, and lung, and small intestine. Trace amounts in cerebellum, dorsal root ganglia, hippocampus, hypothalamus, liver, medulla, pancreas, pituitary, pontine reticular formation, prostate, skeletal muscle and spleen. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs8192618 rs6926857 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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