Gene Information
Gene NameEN2
OrganismHomo sapiens (Human)
Gene Length333
Protein NamesHomeobox protein engrailed-2 (Homeobox protein en-2) (Hu-En-2)
Target Namehomeobox protein engrailed-2
Target TypeNA
Gene Age454 ( ENSG00000164778 )
Evolutionary StageEumetazoa
AlphaFoldDBP19622
Gene CardEN2
Uniprot IDP19622
PfamPF10525; PF00046
In ASDno
Allosteric Predictionno (-0.601370758)
Ortholog in AnimalsAlpaca_ EN2 ( ortholog_one2many )
Dog_ EN2 ( ortholog_one2one )
GuineaPig_ EN2 ( ortholog_one2one )
Macaque_ EN2 ( ortholog_one2one )
Mouse_ En2 ( ortholog_one2one )
Pig_ EN2 ( ortholog_one2one )
Rat_ En2 ( ortholog_one2one )
Rabbit_ EN2 ( ortholog_one2one )
OhnologsNA
ParalogsEN1, CPHXL2, CPHXL
Tissuecerebellar.hemisphere, cerebellum
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.15(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs3735653 
Subcellular location [CC]Nucleus.
Mouse PG classificationNA
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