Gene Information
Gene NameENTPD2
OrganismHomo sapiens (Human)
Gene Length495
Protein NamesEctonucleoside triphosphate diphosphohydrolase 2 (NTPDase 2) (EC 3.6.1.-) (CD39 antigen-like 1) (Ecto-ATP diphosphohydrolase 2) (Ecto-ATPDase 2) (Ecto-ATPase 2)
Target NameNA
Target TypeNA
Gene Age645 ( ENSG00000054179 )
Evolutionary StageEukaryota
AlphaFoldDBQ9Y5L3
Gene CardENTPD2
Uniprot IDQ9Y5L3
PfamPF01150
In ASDno
Allosteric Predictionyes (0.119273495)
Ortholog in AnimalsAlpaca_ ENTPD2 ( ortholog_one2one )
Dog_ ENTPD2 ( ortholog_one2one )
GuineaPig_ ENTPD2 ( ortholog_one2one )
Macaque_ ENTPD2 ( ortholog_one2one )
Mouse_ Entpd2 ( ortholog_one2one )
Pig_ ENTPD2 ( ortholog_one2one )
Rat_ Npdc1 ( ortholog_one2one )
OhnologsNA
ParalogsENTPD8, ENTPD1, ENTPD3, ENTPD5, ENTPD6, ENTPD4, ENTPD7
Tissuebrain, sigmoid.colon, small.intestine, testis
Tissue SpecificityBrain, placenta, skeletal muscle, kidney, pancreas, heart, ovary, testis, colon, small intestine, prostate and pancreas. No expression in adult thymus, spleen, lung, liver and peripheral blood leukocytes.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs34618694 
Subcellular location [CC][Isoform Long]: Cell membrane;
Multi-pass membrane protein.;
[Isoform Short]: Endoplasmic reticulum membrane;
Multi-pass membrane protein.;
[Isoform gamma]: Endoplasmic reticulum membrane;
Multi-pass membrane protein.
Mouse PG classificationNA
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