| Gene Information | |
|---|---|
| Gene Name | CSN2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 443 |
| Protein Names | COP9 signalosome complex subunit 2 (SGN2) (Signalosome subunit 2) (Alien homolog) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (TR-interacting protein 15) (TRIP-15) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000135222 ) 3 ( ENSG00000283030 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | P61201 |
| Gene Card | COPS2 |
| Uniprot ID | P61201 |
| Pfam | PF01399 |
| In ASD | no |
| Allosteric Prediction | yes (0.237436909) |
| Ortholog in Animals | Alpaca_ CSN2 ( ortholog_one2one ) Dog_ CSN2 ( ortholog_one2one ) Macaque_ CSN2 ( ortholog_one2one ) Mouse_ Csn2 ( ortholog_one2one ) Pig_ CSN2 ( ortholog_one2one ) Rat_ Csn2 ( ortholog_one2one ) Rabbit_ CSN2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.017756(Chimpanzee);0.020908(Mouse);NULL(Rat);0.045916(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4D10 (X-ray 3.80A ) 4D18 (X-ray 4.08A ) 4WSN (X-ray 5.50A ) 6A73 (X-ray 2.45A ) 6R6H (EM 8.40A ) 6R7F (EM 8.20A ) 6R7H (EM 8.80A ) 6R7I (EM 5.90A ) 6R7N (EM 6.50A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:9535219}. Nucleus {ECO:0000269|PubMed:10207062}. |
| Mouse PG classification | NA |
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