| Gene Information | |
|---|---|
| Gene Name | NEURL1B |
| Organism | Homo sapiens (Human) |
| Gene Length | 555 |
| Protein Names | E3 ubiquitin-protein ligase NEURL1B (EC 2.3.2.27) (Neuralized-2) (NEUR2) (Neuralized-like protein 1B) (Neuralized-like protein 3) (RING-type E3 ubiquitin transferase NEURL1B) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000214357 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | A8MQ27 |
| Gene Card | NEURL1B |
| Uniprot ID | A8MQ27 |
| Pfam | PF07177 |
| In ASD | no |
| Allosteric Prediction | no (-1.508821169) |
| Ortholog in Animals | Alpaca_ NEURL1B ( ortholog_one2one ) Dog_ NEURL1B ( ortholog_one2one ) GuineaPig_ NEURL1B ( ortholog_one2one ) Macaque_ NEURL1B ( ortholog_one2one ) Mouse_ Neurl1b ( ortholog_one2one ) Pig_ NEURL1B ( ortholog_one2one ) Rat_ Neurl1b ( ortholog_one2one ) Rabbit_ NEURL1B ( ortholog_one2one ) |
| Ohnologs | NEURL1 |
| Paralogs | NEURL3, NEURL1, NEURL4 |
| Tissue | NA |
| Tissue Specificity | Highest expression in brain, prostate and small intestine. In the brain the levels are higher in fetal than in adult stage. In the adult brain the highest levels are detected in the olfactory system, cerebellar cortex, optic nerve and the frontal lobe. {ECO:0000269|PubMed:19723503}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.072727(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:19723503}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |