| Gene Information | |
|---|---|
| Gene Name | EMC2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 297 |
| Protein Names | ER membrane protein complex subunit 2 (Tetratricopeptide repeat protein 35) (TPR repeat protein 35) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000104412 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q15006 |
| Gene Card | EMC2 |
| Uniprot ID | Q15006 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.12831074) |
| Ortholog in Animals | Alpaca_ EMC2 ( ortholog_one2one ) Dog_ EMC2 ( ortholog_one2many ) GuineaPig_ EMC2 ( ortholog_one2one ) Macaque_ EMC2 ( ortholog_one2one ) Mouse_ Emc2 ( ortholog_one2one ) Pig_ EMC2 ( ortholog_one2one ) Rat_ Emc2 ( ortholog_one2one ) Rabbit_ EMC2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6WW7 (EM 3.40A ) 6Y4L (X-ray 2.20A ) 6Z3W (EM 6.40A ) 7ADO (EM 3.39A ) 7ADP (EM 3.60A ) |
| DBSNP | NA |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:22119785}; Peripheral membrane protein {ECO:0000269|PubMed:32439656, ECO:0000269|PubMed:32459176}; Cytoplasmic side {ECO:0000269|PubMed:22119785, ECO:0000269|PubMed:32439656}. Note=May also localize to the nuclear envelope. {ECO:0000250|UniProtKB:Q9CRD2}. |
| Mouse PG classification | NA |
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