| Gene Information | |
|---|---|
| Gene Name | EMAPL1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 815 |
| Protein Names | Echinoderm microtubule-associated protein-like 1 (EMAP-1) (HuEMAP-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O00423 |
| Gene Card | EML1 |
| Uniprot ID | O00423 |
| Pfam | PF03451; PF00400 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous; expressed in most tissues with the exception of thymus and peripheral blood lymphocytes. {ECO:0000269|PubMed:10521658}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4CI8 (X-ray 2.60A ) |
| DBSNP | rs886037937 rs886037936 rs34198557 rs17853154 rs2250718 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250|UniProtKB:Q05BC3}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q05BC3}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:24859200, ECO:0000269|PubMed:25740311}. Note=Detected in cytoplasmic punctae. Co-localizes with microtubules (PubMed:24859200, PubMed:25740311). Enriched in perinuclear regions during interphase and in the region of spindle microtubules during metaphase. Enriched at the midzone during telophase and cytokinesis. Detected at growth cones in neurons (By similarity). {ECO:0000250|UniProtKB:Q05BC3, ECO:0000269|PubMed:24859200, ECO:0000269|PubMed:25740311}. |
| Mouse PG classification | NA |
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