| Gene Information | |
|---|---|
| Gene Name | ELP3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 547 |
| Protein Names | Elongator complex protein 3 (hELP3) (EC 2.3.1.-) (tRNA uridine(34) acetyltransferase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000134014 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q9H9T3 |
| Gene Card | ELP3 |
| Uniprot ID | Q9H9T3 |
| Pfam | PF00583; PF04055; PF16199 |
| In ASD | no |
| Allosteric Prediction | no (-0.962582292) |
| Ortholog in Animals | Alpaca_ ELP3 ( ortholog_one2one ) Dog_ ELP3 ( ortholog_one2one ) GuineaPig_ ELP3 ( ortholog_one2one ) Macaque_ ELP3 ( ortholog_one2one ) Mouse_ Elp3 ( ortholog_one2one ) Pig_ ELP3 ( ortholog_one2one ) Rat_ Elp3 ( ortholog_one2one ) Rabbit_ ELP3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in the cerebellum and spinal motor neurons. {ECO:0000269|PubMed:18996918}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.282433(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:11818576, ECO:0000269|PubMed:19185337, ECO:0000269|PubMed:22854966}. Nucleus {ECO:0000269|PubMed:11714725, ECO:0000269|PubMed:11818576, ECO:0000269|PubMed:22854966}.; [Isoform 1]: Nucleus {ECO:0000269|PubMed:22002106}.; [Isoform 2]: Cytoplasm {ECO:0000269|PubMed:22002106}. Nucleus {ECO:0000269|PubMed:22002106}. |
| Mouse PG classification | NA |
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