| Gene Information | |
|---|---|
| Gene Name | PTGER2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 488 |
| Protein Names | Prostaglandin E2 receptor EP4 subtype (PGE receptor EP4 subtype) (PGE2 receptor EP4 subtype) (Prostanoid EP4 receptor) |
| Target Name | prostaglandin e2 receptor ep2 subtype |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000125384 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P35408 |
| Gene Card | PTGER4 |
| Uniprot ID | P35408 |
| Pfam | PF00001 |
| In ASD | yes |
| Allosteric Prediction | yes (0.999995244) |
| Ortholog in Animals | Alpaca_ PTGER2 ( ortholog_one2one ) Dog_ PTGER2 ( ortholog_one2one ) GuineaPig_ PTGER2 ( ortholog_one2one ) Macaque_ PTGER2 ( ortholog_one2one ) Mouse_ Ptger2 ( ortholog_one2one ) Pig_ PTGER2 ( ortholog_one2one ) Rat_ Ptger2 ( ortholog_one2one ) Rabbit_ PTGER2 ( ortholog_one2one ) |
| Ohnologs | PTGIR |
| Paralogs | PTGDR, PTGIR, PTGER4, PTGER3, PTGFR, TBXA2R, PTGER1 |
| Tissue | NA |
| Tissue Specificity | High in intestine and in peripheral blood mononuclear cells; low in lung, kidney, thymus, uterus, vasculature and brain. Not found in liver, heart, retina oe skeletal muscle. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 5YHL (X-ray 4.20A ) 5YWY (X-ray 3.20A ) 7D7M (EM 3.30A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | LPG |
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