| Gene Information | |
|---|---|
| Gene Name | ELMO2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 720 |
| Protein Names | Engulfment and cell motility protein 2 (Protein ced-12 homolog A) (hCed-12A) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000062598 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q96JJ3 |
| Gene Card | ELMO2 |
| Uniprot ID | Q96JJ3 |
| Pfam | PF11841; PF04727; PF16457 |
| In ASD | no |
| Allosteric Prediction | no (-0.443174963) |
| Ortholog in Animals | Alpaca_ ELMO2 ( ortholog_one2one ) Dog_ ELMO2 ( ortholog_one2one ) GuineaPig_ ELMO2 ( ortholog_one2one ) Macaque_ ELMO2 ( ortholog_one2one ) Mouse_ Elmo2 ( ortholog_one2one ) Pig_ ELMO2 ( ortholog_one2one ) Rat_ Elmo2 ( ortholog_one2one ) Rabbit_ ELMO2 ( ortholog_one2one ) |
| Ohnologs | ELMO3 |
| Paralogs | ELMO3, ELMOD3, ELMOD1, ELMO1, ELMOD2 |
| Tissue | NA |
| Tissue Specificity | Widely expressed, with a higher expression in skeletal muscle, kidney and placenta. {ECO:0000269|PubMed:11595183}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6IDX (X-ray 1.70A ) 6IE1 (X-ray 2.48A ) |
| DBSNP | rs34630674 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:20679435}. Cytoplasm, cytosol {ECO:0000269|PubMed:20679435}. Membrane {ECO:0000269|PubMed:20679435}. |
| Mouse PG classification | NA |
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