| Gene Information | |
|---|---|
| Gene Name | ELMO1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 727 |
| Protein Names | Engulfment and cell motility protein 1 (Protein ced-12 homolog) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000155849 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q92556 |
| Gene Card | ELMO1 |
| Uniprot ID | Q92556 |
| Pfam | PF11841; PF04727; PF16457 |
| In ASD | no |
| Allosteric Prediction | no (-0.109350415) |
| Ortholog in Animals | Alpaca_ ELMO1 ( ortholog_one2one ) Dog_ ELMO1 ( ortholog_one2one ) GuineaPig_ ELMO1 ( ortholog_one2one ) Macaque_ ELMO1 ( ortholog_one2one ) Mouse_ Elmo1 ( ortholog_one2one ) Pig_ ELMO1 ( ortholog_one2one ) Rat_ Elmo1 ( ortholog_one2one ) Rabbit_ ELMO1 ( ortholog_one2one ) |
| Ohnologs | ELMO3 |
| Paralogs | ELMO2, ELMO3, ELMOD3, ELMOD1, ELMOD2 |
| Tissue | NA |
| Tissue Specificity | Widely expressed, with a higher expression in the spleen and placenta. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.030769(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2RQR (NMR - ) 2VSZ (X-ray 2.30A ) 3A98 (X-ray 2.10A ) 6JPP (NMR - ) 6TGB (EM 5.50A ) 6TGC (EM 4.10A ) 7DPA (EM 3.80A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm. Cell membrane. Note=Translocation to plasma membrane seems to be mediated by DOCK1 and CRK. |
| Mouse PG classification | NA |
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