| Gene Information | |
|---|---|
| Gene Name | ELAC1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 363 |
| Protein Names | Zinc phosphodiesterase ELAC protein 1 (EC 3.1.26.11) (Deleted in Ma29) (ElaC homolog protein 1) (Ribonuclease Z 1) (RNase Z 1) (tRNA 3 endonuclease 1) (tRNase Z 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000141642 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q9H777 |
| Gene Card | ELAC1 |
| Uniprot ID | Q9H777 |
| Pfam | PF00753; PF12706 |
| In ASD | no |
| Allosteric Prediction | no (-1.747678235) |
| Ortholog in Animals | Alpaca_ ELAC1 ( ortholog_one2one ) Dog_ SMAD4 ( ortholog_one2one ) GuineaPig_ ELAC1 ( ortholog_one2one ) Macaque_ ELAC1 ( ortholog_one2one ) Mouse_ Elac1 ( ortholog_one2one ) Pig_ ELAC1 ( ortholog_one2one ) Rat_ Elac1 ( ortholog_one2one ) Rabbit_ ELAC1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ELAC2 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:11401430}. |
| Pharmacological Animal Models | 0.039269(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 3ZWF (X-ray 1.70A ) |
| DBSNP | rs34524743 |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000269|PubMed:21593607}. Nucleus {ECO:0000269|PubMed:21593607}. Note=Mainly cytosolic. |
| Mouse PG classification | NA |
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