| Gene Information | |
|---|---|
| Gene Name | EIF5B |
| Organism | Homo sapiens (Human) |
| Gene Length | 1220 |
| Protein Names | Eukaryotic translation initiation factor 5B (eIF-5B) (EC 3.6.5.3) (Translation initiation factor IF-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000158417 ) |
| Evolutionary Stage | Euk_Archaea |
| AlphaFoldDB | O60841 |
| Gene Card | EIF5B |
| Uniprot ID | O60841 |
| Pfam | PF00009; PF03144; PF11987 |
| In ASD | no |
| Allosteric Prediction | no (-0.385439663) |
| Ortholog in Animals | Alpaca_ EIF5B ( ortholog_one2one ) Dog_ EIF5B ( ortholog_one2one ) Macaque_ EIF5B ( ortholog_one2one ) Mouse_ Eif5b ( ortholog_one2one ) Pig_ EIF5B ( ortholog_one2one ) Rat_ Eif5b ( ortholog_one2one ) Rabbit_ EIF5B ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | EFTUD2, EIF2S3, EIF2S3B, GTPBP1, GUF1, MTIF2, EEF2, EFL1, GSPT2, EEFSEC, EEF1A1, EEF1A2, HBS1L, GTPBP2, GFM2, GFM1, GSPT1, TUFM |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.045343(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7TQL (EM 3.40A ) |
| DBSNP | rs10642 rs3205296 rs7558074 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250|UniProtKB:Q05D44}. |
| Mouse PG classification | NA |
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