| Gene Information | |
|---|---|
| Gene Name | SLC39A6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 755 |
| Protein Names | Zinc transporter ZIP6 (Estrogen-regulated protein LIV-1) (Solute carrier family 39 member 6) (Zrt- and Irt-like protein 6) (ZIP-6) |
| Target Name | solute carrier family 39 member 6 |
| Target Type | Clinical trial target |
| Gene Age | 987 ( ENSG00000141424 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q13433 |
| Gene Card | SLC39A6 |
| Uniprot ID | Q13433 |
| Pfam | PF02535 |
| In ASD | no |
| Allosteric Prediction | yes (0.035332327) |
| Ortholog in Animals | Alpaca_ SLC39A6 ( ortholog_one2one ) Dog_ SLC39A6 ( ortholog_one2one ) GuineaPig_ SLC39A6 ( ortholog_one2one ) Macaque_ SLC39A6 ( ortholog_one2one ) Mouse_ Slc39a6 ( ortholog_one2one ) Pig_ SLC39A6 ( ortholog_one2one ) Rat_ Slc39a6 ( ortholog_one2one ) Rabbit_ SLC39A6 ( ortholog_one2one ) |
| Ohnologs | SLC39A14, SLC39A10 |
| Paralogs | SLC39A4, SLC39A8, SLC39A5, SLC39A10, SLC39A12, SLC39A14 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in the breast, prostate, placenta, kidney, pituitary and corpus callosum. Weakly expressed in heart and intestine. Also highly expressed in cells derived from an adenocarcinoma of the cervix and lung carcinoma. {ECO:0000269|PubMed:12839489}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs1789528 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:12839489}; Multi-pass membrane protein {ECO:0000269|PubMed:12839489}. |
| Mouse PG classification | NA |
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