| Gene Information | |
|---|---|
| Gene Name | SYCP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 976 |
| Protein Names | Synaptonemal complex protein 1 (SCP-1) (Cancer/testis antigen 8) (CT8) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000198765 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q15431 |
| Gene Card | SYCP1 |
| Uniprot ID | Q15431 |
| Pfam | PF05483 |
| In ASD | no |
| Allosteric Prediction | no (-0.220374051) |
| Ortholog in Animals | Alpaca_ SYCP1 ( ortholog_one2one ) Dog_ SYCP1 ( ortholog_one2one ) GuineaPig_ SYCP1 ( ortholog_one2one ) Macaque_ SYCP1 ( ortholog_one2one ) Mouse_ Sycp1 ( ortholog_one2one ) Pig_ SYCP1 ( ortholog_one2one ) Rat_ Sycp1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | testis |
| Tissue Specificity | Testis. {ECO:0000269|PubMed:9371398}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4YTO (X-ray 2.00A ) 6F5X (X-ray 1.91A ) 6F62 (X-ray 2.07A ) 6F63 (X-ray 2.15A ) 6F64 (X-ray 2.49A ) |
| DBSNP | rs12563933 rs1053812 |
| Subcellular location [CC] | Nucleus {ECO:0000250|UniProtKB:Q62209}. Chromosome {ECO:0000250|UniProtKB:Q62209}. Chromosome, centromere {ECO:0000250|UniProtKB:Q62209}. Note=In tripartite segments of synaptonemal complexes, between lateral elements in the nucleus. Its N-terminus is found towards the center of the synaptonemal complex while the C-terminus extends well into the lateral domain of the synaptonemal complex (By similarity). Only rarely detected at centromeres during leptotene and zygotene. Detected at centromeres during mid-diplotene, when it is no longer present along chromosome arms. No longer detected at centromeres at later stages of meiosis (By similarity). {ECO:0000250|UniProtKB:Q03410, ECO:0000250|UniProtKB:Q62209}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |