| Gene Information | |
|---|---|
| Gene Name | KIAA0245 |
| Organism | Homo sapiens (Human) |
| Gene Length | 515 |
| Protein Names | Y+L amino acid transporter 2 (Cationic amino acid transporter, y+ system) (Solute carrier family 7 member 6) (y(+)L-type amino acid transporter 2) (Y+LAT2) (y+LAT-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q92536 |
| Gene Card | SLC7A6 |
| Uniprot ID | Q92536 |
| Pfam | PF13520 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in normal fibroblasts and those from LPI patients. Also expressed in HUVECs, monocytes, RPE cells, and various carcinoma cell lines. {ECO:0000269|PubMed:11078698, ECO:0000269|PubMed:11742806, ECO:0000269|PubMed:14603368, ECO:0000269|PubMed:15280038, ECO:0000269|PubMed:17197568, ECO:0000269|PubMed:17329401}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Basolateral cell membrane {ECO:0000269|PubMed:15756301, ECO:0000269|PubMed:16785209}; Multi-pass membrane protein {ECO:0000269|PubMed:15756301, ECO:0000269|PubMed:16785209}. |
| Mouse PG classification | NA |
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