| Gene Information | |
|---|---|
| Gene Name | EIF4EBP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 118 |
| Protein Names | Eukaryotic translation initiation factor 4E-binding protein 1 (4E-BP1) (eIF4E-binding protein 1) (Phosphorylated heat- and acid-stable protein regulated by insulin 1) (PHAS-I) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000187840 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q13541 |
| Gene Card | EIF4EBP1 |
| Uniprot ID | Q13541 |
| Pfam | PF05456 |
| In ASD | no |
| Allosteric Prediction | no (-0.10106623) |
| Ortholog in Animals | Dog_ EIF4EBP1 ( ortholog_one2one ) GuineaPig_ EIF4EBP1 ( ortholog_one2one ) Macaque_ EIF4EBP1 ( ortholog_one2one ) Mouse_ Eif4ebp1 ( ortholog_one2one ) Pig_ EIF4EBP1 ( ortholog_one2one ) Rat_ Eif4ebp1 ( ortholog_one2one ) Rabbit_ EIF4EBP1 ( ortholog_one2one ) |
| Ohnologs | EIF4EBP2 |
| Paralogs | EIF4EBP3, EIF4EBP2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001425(Rat);0.017391(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1EJ4 (X-ray 2.25A ) 1EJH (X-ray 2.20A ) 1WKW (X-ray 2.10A ) 2JGB (X-ray 1.70A ) 2JGC (X-ray 2.40A ) 2V8W (X-ray 2.30A ) 2V8X (X-ray 2.30A ) 2V8Y (X-ray 2.10A ) 3HXG (X-ray 2.10A ) 3HXI (X-ray 1.80A ) 3M93 (X-ray 2.90A ) 3M94 (X-ray 2.05A ) 3U7X (X-ray 2.10A ) 4UED (X-ray 1.75A ) 5BXV (X-ray 2.10A ) 5EKV (X-ray 3.61A ) 5NVN (X-ray 1.90A ) 5WBJ (X-ray 3.00A ) 6BCU (EM 3.43A ) 6BCX (EM 3.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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