| Gene Information | |
|---|---|
| Gene Name | EIF3M |
| Organism | Homo sapiens (Human) |
| Gene Length | 374 |
| Protein Names | Eukaryotic translation initiation factor 3 subunit M (eIF3m) (Fetal lung protein B5) (hFL-B5) (PCI domain-containing protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000149100 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q7L2H7 |
| Gene Card | EIF3M |
| Uniprot ID | Q7L2H7 |
| Pfam | PF18005; PF01399 |
| In ASD | no |
| Allosteric Prediction | no (-0.614055822) |
| Ortholog in Animals | Alpaca_ EIF3M ( ortholog_one2one ) Dog_ EIF3M ( ortholog_one2one ) GuineaPig_ EIF3M ( ortholog_one2one ) Macaque_ EIF3M ( ortholog_one2one ) Mouse_ Eif3m ( ortholog_one2one ) Pig_ EIF3M ( ortholog_one2one ) Rat_ Eif3m ( ortholog_one2one ) Rabbit_ EIF3M ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | COPS7A, COPS7B |
| Tissue | NA |
| Tissue Specificity | Broadly expressed. {ECO:0000269|PubMed:15919898}. |
| Pharmacological Animal Models | 0.013288(Chimpanzee);0.315239(Mouse);0.072580(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 3J8B (EM - ) 3J8C (EM - ) 6FEC (EM 6.30A ) 6YBD (EM 3.30A ) 6ZMW (EM 3.70A ) 6ZON (EM 3.00A ) 6ZP4 (EM 2.90A ) 6ZVJ (EM 3.80A ) 7A09 (EM 3.50A ) 7QP6 (EM 4.70A ) 7QP7 (EM 3.70A ) |
| DBSNP | rs11557143 rs1802363 |
| Subcellular location [CC] | Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03012}. |
| Mouse PG classification | NA |
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