| Gene Information | |
|---|---|
| Gene Name | EIF3G |
| Organism | Homo sapiens (Human) |
| Gene Length | 320 |
| Protein Names | Eukaryotic translation initiation factor 3 subunit G (eIF3g) (Eukaryotic translation initiation factor 3 RNA-binding subunit) (eIF-3 RNA-binding subunit) (Eukaryotic translation initiation factor 3 subunit 4) (eIF-3-delta) (eIF3 p42) (eIF3 p44) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000130811 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O75821 |
| Gene Card | EIF3G |
| Uniprot ID | O75821 |
| Pfam | PF12353; PF00076 |
| In ASD | no |
| Allosteric Prediction | no (-0.262947474) |
| Ortholog in Animals | Alpaca_ EIF3G ( ortholog_one2one ) Dog_ EIF3G ( ortholog_one2one ) GuineaPig_ EIF3G ( ortholog_one2one ) Macaque_ EIF3G ( ortholog_one2one ) Mouse_ Eif3g ( ortholog_one2one ) Pig_ EIF3G ( ortholog_one2one ) Rat_ Eif3g ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2CQ0 (NMR - ) 2MJC (NMR - ) 5K0Y (EM 5.80A ) 6YBS (EM 3.10A ) 6ZMW (EM 3.70A ) 7QP6 (EM 4.70A ) 7QP7 (EM 3.70A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03006}. Nucleus {ECO:0000255|HAMAP-Rule:MF_03006, ECO:0000269|PubMed:17094969}. Cytoplasm, perinuclear region {ECO:0000255|HAMAP-Rule:MF_03006, ECO:0000269|PubMed:17094969}. Note=Colocalizes with AIFM1 in the nucleus and perinuclear region. |
| Mouse PG classification | NA |
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