| Gene Information | |
|---|---|
| Gene Name | EIF3B |
| Organism | Homo sapiens (Human) |
| Gene Length | 814 |
| Protein Names | Eukaryotic translation initiation factor 3 subunit B (eIF3b) (Eukaryotic translation initiation factor 3 subunit 9) (Prt1 homolog) (hPrt1) (eIF-3-eta) (eIF3 p110) (eIF3 p116) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 18 ( ENSG00000106263 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P55884 |
| Gene Card | EIF3B |
| Uniprot ID | P55884 |
| Pfam | PF08662; PF00076 |
| In ASD | no |
| Allosteric Prediction | no (-0.261471005) |
| Ortholog in Animals | Alpaca_ EIF3B ( ortholog_one2many ) Dog_ EIF3B ( ortholog_one2one ) Macaque_ EIF3B ( ortholog_one2one ) Mouse_ Eif3b ( ortholog_one2one ) Pig_ EIF3B ( ortholog_one2one ) Rat_ Eif3b ( ortholog_one2one ) Rabbit_ EIF3B ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.072532(Rat);0.058292(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2KRB (NMR - ) 2NLW (NMR - ) 5K1H (EM 4.90A ) 6YBT (EM 6.00A ) 6ZMW (EM 3.70A ) 6ZON (EM 3.00A ) 6ZP4 (EM 2.90A ) 6ZVJ (EM 3.80A ) 7A09 (EM 3.50A ) 7QP6 (EM 4.70A ) 7QP7 (EM 3.70A ) |
| DBSNP | rs9690787 rs1063257 |
| Subcellular location [CC] | Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03001}. Cytoplasm, Stress granule {ECO:0000269|PubMed:17984221}. Note=Localizes to stress granules following cellular stress. {ECO:0000269|PubMed:17984221}. |
| Mouse PG classification | NA |
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