| Gene Information | |
|---|---|
| Gene Name | ST6GALNAC3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 305 |
| Protein Names | Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 (EC 2.4.3.7) (GalNAc alpha-2,6-sialyltransferase III) (ST6GalNAc III) (ST6GalNAcIII) (STY) (Sialyltransferase 7C) (SIAT7-C) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000184005 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q8NDV1 |
| Gene Card | ST6GALNAC3 |
| Uniprot ID | Q8NDV1 |
| Pfam | PF00777 |
| In ASD | no |
| Allosteric Prediction | no (-1.401788703) |
| Ortholog in Animals | Alpaca_ ST6GALNAC3 ( ortholog_one2one ) Dog_ ST6GALNAC3 ( ortholog_one2one ) GuineaPig_ ST6GALNAC3 ( ortholog_one2one ) Macaque_ ST6GALNAC3 ( ortholog_one2one ) Mouse_ St6galnac3 ( ortholog_one2one ) Pig_ ST6GALNAC3 ( ortholog_one2one ) Rat_ St6galnac3 ( ortholog_one2one ) |
| Ohnologs | ST6GALNAC4 |
| Paralogs | ST6GALNAC5, C20orf173, ST3GAL4, ST3GAL3, ST3GAL2, ST6GAL1, ST6GALNAC4, ST6GALNAC6, ST6GALNAC2, ST3GAL5, ST3GAL6, ST6GAL2, ST6GALNAC1, ST3GAL1 |
| Tissue | NA |
| Tissue Specificity | Expressed in brain and kidney (PubMed:16169874, PubMed:17123352). Observed in the epithelium of the proximal tubules, marginal expression was also found in the distal tubules and collecting tubules (PubMed:17123352). {ECO:0000269|PubMed:16169874, ECO:0000269|PubMed:17123352}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs1184626 |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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