| Gene Information | |
|---|---|
| Gene Name | EIF2B2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 351 |
| Protein Names | Translation initiation factor eIF-2B subunit beta (S20I15) (S20III15) (eIF-2B GDP-GTP exchange factor subunit beta) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000119718 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P49770 |
| Gene Card | EIF2B2 |
| Uniprot ID | P49770 |
| Pfam | PF01008 |
| In ASD | no |
| Allosteric Prediction | yes (0.07134521) |
| Ortholog in Animals | Alpaca_ EIF2B2 ( ortholog_one2one ) Dog_ EIF2B2 ( ortholog_one2one ) GuineaPig_ EIF2B2 ( ortholog_one2one ) Macaque_ EIF2B2 ( ortholog_one2one ) Mouse_ Eif2b2 ( ortholog_one2one ) Pig_ EIF2B2 ( ortholog_one2one ) Rat_ Eif2b2 ( ortholog_one2one ) Rabbit_ EIF2B2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MRI1, EIF2B4, EIF2B1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.044560(Chimpanzee);0.243661(Mouse);0.290107(Rat);0.177788(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6CAJ (EM 2.80A ) 6EZO (EM 4.10A ) 6K71 (EM 4.30A ) 6K72 (EM 4.60A ) 6O81 (EM 3.21A ) 6O85 (EM 3.03A ) 6O9Z (EM 3.03A ) 7D43 (EM 4.30A ) 7D44 (EM 4.00A ) 7D45 (EM 3.80A ) 7D46 (EM 4.00A ) 7F64 (EM 2.42A ) 7F66 (EM 2.76A ) 7F67 (EM 3.59A ) 7KMF (EM 2.91A ) 7L70 (EM 2.80A ) 7L7G (EM 3.00A ) 7RLO (EM 2.60A ) 7TRJ (EM 2.80A ) 7VLK (EM 2.27A ) |
| DBSNP | rs397514648 rs150617429 rs104894428 rs113994011 rs113994012 rs104894425 rs113994016 rs104894426 rs113994020 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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