| Gene Information | |
|---|---|
| Gene Name | EIF2B1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 305 |
| Protein Names | Translation initiation factor eIF-2B subunit alpha (eIF-2B GDP-GTP exchange factor subunit alpha) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000111361 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q14232 |
| Gene Card | EIF2B1 |
| Uniprot ID | Q14232 |
| Pfam | PF01008 |
| In ASD | no |
| Allosteric Prediction | no (-0.233763563) |
| Ortholog in Animals | Alpaca_ EIF2B1 ( ortholog_one2one ) Dog_ EIF2B1 ( ortholog_one2one ) GuineaPig_ EIF2B1 ( ortholog_one2one ) Macaque_ EIF2B1 ( ortholog_one2one ) Mouse_ Eif2b1 ( ortholog_one2one ) Rat_ Eif2b1 ( ortholog_one2one ) Rabbit_ EIF2B1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MRI1, EIF2B4, EIF2B2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.185683(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3ECS (X-ray 2.65A ) 6CAJ (EM 2.80A ) 6EZO (EM 4.10A ) 6K71 (EM 4.30A ) 6K72 (EM 4.60A ) 6O81 (EM 3.21A ) 6O85 (EM 3.03A ) 6O9Z (EM 3.03A ) 7D43 (EM 4.30A ) 7D44 (EM 4.00A ) 7D45 (EM 3.80A ) 7D46 (EM 4.00A ) 7F64 (EM 2.42A ) 7F66 (EM 2.76A ) 7F67 (EM 3.59A ) 7KMA (X-ray 2.70A ) 7KMF (EM 2.91A ) 7L70 (EM 2.80A ) 7L7G (EM 3.00A ) 7RLO (EM 2.60A ) 7TRJ (EM 2.80A ) 7VLK (EM 2.27A ) |
| DBSNP | rs863225048 rs113994007 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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