Gene Information
Gene NameEID1
OrganismHomo sapiens (Human)
Gene Length187
Protein NamesEP300-interacting inhibitor of differentiation 1 (21 kDa pRb-associated protein) (CREBBP/EP300 inhibitory protein 1) (E1A-like inhibitor of differentiation 1) (EID-1)
Target NameNA
Target TypeNA
Gene Age93 ( ENSG00000255302 )
Evolutionary StageMammalia
AlphaFoldDBQ9Y6B2
Gene CardEID1
Uniprot IDQ9Y6B2
PfamNA
In ASDno
Allosteric Predictionno (-1.002584809)
Ortholog in AnimalsAlpaca_ EID1 ( ortholog_one2one )
Dog_ EID1 ( ortholog_one2one )
GuineaPig_ EID1 ( ortholog_one2one )
Mouse_ Eid1 ( ortholog_one2one )
Pig_ EID1 ( ortholog_one2one )
Rat_ Eid1 ( ortholog_one2one )
Rabbit_ EID1 ( ortholog_one2one )
OhnologsNA
ParalogsEID2, EID2B
TissueNA
Tissue SpecificityWidely expressed. Most abundantly expressed in heart, skeletal muscle, pancreas, brain and testis. Expressed at much lower levels in placenta and peripheral blood leukocyte. Barely detectable in lung. Also weakly expressed in lung carcinoma A-549 and various leukemia cell lines. {ECO:0000269|PubMed:11073990, ECO:0000269|PubMed:11223246}.
Pharmacological Animal ModelsNULL(Chimpanzee);0.032468(Mouse);0.003490(Rat);0.022222(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 7SMD  (X-ray  2.15A 
DBSNP NA 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:11223246}. Cytoplasm {ECO:0000269|PubMed:11223246}. Note=May shuttle between nucleus and cytoplasm. {ECO:0000250|UniProtKB:Q9DCR4, ECO:0000269|PubMed:11223246}.
Mouse PG classificationNA
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