| Gene Information | |
|---|---|
| Gene Name | EHF |
| Organism | Homo sapiens (Human) |
| Gene Length | 300 |
| Protein Names | ETS homologous factor (hEHF) (ETS domain-containing transcription factor) (Epithelium-specific Ets transcription factor 3) (ESE-3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000135373 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9NZC4 |
| Gene Card | EHF |
| Uniprot ID | Q9NZC4 |
| Pfam | PF00178; PF02198 |
| In ASD | no |
| Allosteric Prediction | no (-0.89572763) |
| Ortholog in Animals | Alpaca_ EHF ( ortholog_one2one ) Dog_ EHF ( ortholog_one2one ) GuineaPig_ EHF ( ortholog_one2one ) Macaque_ EHF ( ortholog_one2one ) Mouse_ Ehf ( ortholog_one2one ) Pig_ EHF ( ortholog_one2one ) Rat_ Ehf ( ortholog_one2one ) Rabbit_ EHF ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ELK1, ETV6, ERG, ERF, ETV4, ETV7, ELF4, ELF3, ETV2, ETV3L, ETS2, FLI1, GABPA, ETV5, ETV1, ELF5, ETV3, ELK3, ETS1, ELF2, SPI1, ELK4, ELF1, SPIB, FEV, SPIC, ERFL, SPDEF |
| Tissue | small.intestine, esophagus.mucosa, minor.salivary.gland, vagina |
| Tissue Specificity | Expressed exclusively in tissues with a high content of epithelial cells. Highly expressed in salivary gland, mammary gland, prostate, and lung. Weakly expressed in kidney and colon. Not detected in heart, brain, placenta, liver, skeletal muscle, spleen, thymus, testis, ovary, small intestine or peripheral blood leukocytes. {ECO:0000269|PubMed:10527851, ECO:0000269|PubMed:10644770, ECO:0000269|PubMed:11259407, ECO:0000269|PubMed:12444029}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs9804460 |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00237, ECO:0000269|PubMed:11259407, ECO:0000269|PubMed:12444029}. |
| Mouse PG classification | NA |
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