| Gene Information | |
|---|---|
| Gene Name | P2RX6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 441 |
| Protein Names | P2X purinoceptor 6 (P2X6) (ATP receptor) (P2XM) (Purinergic receptor) (Purinergic receptor P2X-like 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 424 ( ENSG00000099957 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | O15547 |
| Gene Card | P2RX6 |
| Uniprot ID | O15547 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | yes (0.358580842) |
| Ortholog in Animals | Alpaca_ P2RX6 ( ortholog_one2many ) Dog_ P2RX6 ( ortholog_one2one ) GuineaPig_ P2RX6 ( ortholog_one2one ) Macaque_ P2RX6 ( ortholog_one2one ) Mouse_ P2rx6 ( ortholog_one2one ) Pig_ P2RX6 ( ortholog_one2one ) Rat_ P2rx6 ( ortholog_one2one ) Rabbit_ P2RX6 ( ortholog_one2one ) |
| Ohnologs | P2RX1, P2RX3, P2RX4 |
| Paralogs | P2RX5, P2RX3, P2RX2, P2RX1, P2RX7, P2RX4 |
| Tissue | NA |
| Tissue Specificity | Expressed predominantly in skeletal muscle. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2006846 rs2277838 |
| Subcellular location [CC] | Membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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