Gene Information
Gene NameEG1
OrganismHomo sapiens (Human)
Gene Length178
Protein NamesMediator of RNA polymerase II transcription subunit 28 (Endothelial-derived protein 1) (Mediator complex subunit 28) (Merlin and Grb2-interacting cytoskeletal protein) (Magicin) (Tumor angiogenesis marker EG-1)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ9H204
Gene CardMED28
Uniprot IDQ9H204
PfamNA
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityWidely expressed. Highly expressed in vascular tissues such as placenta, testis and liver. {ECO:0000269|PubMed:15467741}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.001860(Rat);0.07021(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 7EMF  (EM  3.50A  7ENA  (EM  4.07A  7ENC  (EM  4.13A  7ENJ  (EM  4.40A  7LBM  (EM  4.80A  7NVR  (EM  4.50A 
DBSNP NA 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:15467741}. Cytoplasm {ECO:0000269|PubMed:15467741}. Membrane {ECO:0000269|PubMed:15467741};
Peripheral membrane protein {ECO:0000269|PubMed:15467741}. Note=According to PubMed:15467741, it is cytoplasmic and mainly membrane-associated.
Mouse PG classificationNA
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