Gene Information
Gene NameEFS
OrganismHomo sapiens (Human)
Gene Length561
Protein NamesEmbryonal Fyn-associated substrate (hEFS) (Cas scaffolding protein family member 3)
Target NameNA
Target TypeNA
Gene Age987 ( ENSG00000100842 )
Evolutionary StageEumetazoa
AlphaFoldDBO43281
Gene CardEFS
Uniprot IDO43281
PfamPF12026; PF14604
In ASDno
Allosteric Predictionno (-0.883261691)
Ortholog in AnimalsAlpaca_ EFS ( ortholog_one2one )
Dog_ EFS ( ortholog_one2one )
GuineaPig_ EFS ( ortholog_one2one )
Macaque_ EFS ( ortholog_one2one )
Mouse_ Efs ( ortholog_one2one )
Pig_ EFS ( ortholog_one2one )
Rat_ Efs ( ortholog_one2one )
Rabbit_ EFS ( ortholog_one2one )
OhnologsNA
ParalogsCASS4, NEDD9, BCAR1
TissueNA
Tissue SpecificityThe protein has been detected in lung and placenta.
Pharmacological Animal Models0.000730(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs2231798  rs2231801  rs1463886157 
Subcellular location [CC]NA
Mouse PG classificationNA
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