| Gene Information | |
|---|---|
| Gene Name | EFNB3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 340 |
| Protein Names | Ephrin-B3 (EPH-related receptor transmembrane ligand ELK-L3) (EPH-related receptor tyrosine kinase ligand 8) (LERK-8) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 168 ( ENSG00000108947 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q15768 |
| Gene Card | EFNB3 |
| Uniprot ID | Q15768 |
| Pfam | PF00812 |
| In ASD | no |
| Allosteric Prediction | no (-0.281884648) |
| Ortholog in Animals | Alpaca_ EFNB3 ( ortholog_one2one ) Dog_ EFNB3 ( ortholog_one2one ) GuineaPig_ EFNB3 ( ortholog_one2one ) Macaque_ EFNB3 ( ortholog_one2one ) Mouse_ Efnb3 ( ortholog_one2one ) Pig_ EFNB3 ( ortholog_one2one ) Rat_ Efnb3 ( ortholog_one2one ) Rabbit_ EFNB3 ( ortholog_one2one ) |
| Ohnologs | EFNB1, EFNB2 |
| Paralogs | EFNB2, EFNA2, EFNB1, EFNA1, EFNA3, EFNA4, EFNA5 |
| Tissue | brain, cerebral.cortex, amygdala, brain.meninx, caudate.nucleus, hippocampus, middle.frontal.gyrus, middle.temporal.gyrus, olfactory.apparatus, putamen |
| Tissue Specificity | Highly expressed in brain; expressed in embryonic floor plate, roof plate and hindbrain segments. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.005990(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4BKF (X-ray 4.65A ) |
| DBSNP | rs1165640333 |
| Subcellular location [CC] | Membrane; Single-pass type I membrane protein. |
| Mouse PG classification | NA |
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