Gene Information
Gene NameEFNA3
OrganismHomo sapiens (Human)
Gene Length238
Protein NamesEphrin-A3 (EFL-2) (EHK1 ligand) (EHK1-L) (EPH-related receptor tyrosine kinase ligand 3) (LERK-3)
Target NameNA
Target TypeNA
Gene Age454 ( ENSG00000143590 )
Evolutionary StageEumetazoa
AlphaFoldDBP52797
Gene CardEFNA3
Uniprot IDP52797
PfamPF00812
In ASDno
Allosteric Predictionno (-0.692100999)
Ortholog in AnimalsAlpaca_ EFNA3 ( ortholog_one2one )
Dog_ EFNA3 ( ortholog_one2one )
GuineaPig_ EFNA3 ( ortholog_one2one )
Macaque_ EFNA3 ( ortholog_one2one )
Mouse_ Efna3 ( ortholog_one2one )
Pig_ EFNA3 ( ortholog_one2one )
Rat_ Efna3 ( ortholog_one2one )
Rabbit_ EFNA3 ( ortholog_one2one )
OhnologsEFNA2, EFNA5
ParalogsEFNB2, EFNA2, EFNB3, EFNB1, EFNA1, EFNA4, EFNA5
Tissueskin, lower.leg.skin, suprapubic.skin
Tissue SpecificityExpressed in brain, skeletal muscle, spleen, thymus, prostate, testis, ovary, small intestine, and peripheral blood leukocytes.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs17723260 
Subcellular location [CC]Cell membrane;
Lipid-anchor, GPI-anchor.
Mouse PG classificationNA
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