| Gene Information | |
|---|---|
| Gene Name | EFEMP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 443 |
| Protein Names | EGF-containing fibulin-like extracellular matrix protein 2 (Fibulin-4) (FIBL-4) (Protein UPH1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000172638 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | O95967 |
| Gene Card | EFEMP2 |
| Uniprot ID | O95967 |
| Pfam | PF12662; PF07645 |
| In ASD | no |
| Allosteric Prediction | no (-0.907207792) |
| Ortholog in Animals | Alpaca_ EFEMP2 ( ortholog_one2one ) Dog_ EFEMP2 ( ortholog_one2one ) GuineaPig_ EFEMP2 ( ortholog_one2one ) Macaque_ EFEMP2 ( ortholog_one2one ) Mouse_ Efemp2 ( ortholog_one2one ) Pig_ EFEMP2 ( ortholog_one2one ) Rat_ Efemp2 ( ortholog_one2one ) |
| Ohnologs | FBLN1, FBLN5, EFEMP1, FBLN2 |
| Paralogs | VWDE, EFEMP1, FBLN1, FBLN5, FBLN2, EYS |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2KL7 (NMR - ) |
| DBSNP | rs119489101 rs601314 rs193302866 rs119489102 |
| Subcellular location [CC] | Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:20389311, ECO:0000269|PubMed:27339457}. Secreted, extracellular space, extracellular matrix, basement membrane {ECO:0000250|UniProtKB:Q9WVJ9}. Note=Localizes on the microfibrils surrounding ELN cores. {ECO:0000250|UniProtKB:Q9WVJ9}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |