| Gene Information | |
|---|---|
| Gene Name | EEK |
| Organism | Homo sapiens (Human) |
| Gene Length | 1005 |
| Protein Names | Ephrin type-A receptor 8 (EC 2.7.10.1) (EPH- and ELK-related kinase) (EPH-like kinase 3) (EK3) (hEK3) (Tyrosine-protein kinase receptor EEK) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P29322 |
| Gene Card | EPHA8 |
| Uniprot ID | P29322 |
| Pfam | PF14575; PF01404; PF00041; PF07714; PF00536 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1UCV (NMR - ) 1X5L (NMR - ) 3KUL (X-ray 2.15A ) |
| DBSNP | rs45498698 rs56402644 rs1557556639 rs56656925 rs2295021 rs999765 |
| Subcellular location [CC] | Cell membrane {ECO:0000250|UniProtKB:O09127}; Single-pass type I membrane protein {ECO:0000255}. Cell projection {ECO:0000250|UniProtKB:O09127}. Early endosome membrane {ECO:0000250|UniProtKB:O09127}. Note=Undergoes clathrin-mediated endocytosis upon EFNA5-binding and is targeted to early endosomes. {ECO:0000250|UniProtKB:O09127}. |
| Mouse PG classification | NA |
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