| Gene Information | |
|---|---|
| Gene Name | EEF2K |
| Organism | Homo sapiens (Human) |
| Gene Length | 725 |
| Protein Names | Eukaryotic elongation factor 2 kinase (eEF-2 kinase) (eEF-2K) (EC 2.7.11.20) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase) |
| Target Name | eukaryotic elongation factor 2 kinase |
| Target Type | Successful target |
| Gene Age | 1714 ( ENSG00000103319 ) 3 ( ENSG00000284161 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O00418 |
| Gene Card | EEF2K |
| Uniprot ID | O00418 |
| Pfam | PF02816; PF08238 |
| In ASD | yes |
| Allosteric Prediction | yes (1.000326182) |
| Ortholog in Animals | Alpaca_ EEF2K ( ortholog_one2one ) Dog_ EEF2K ( ortholog_one2one ) GuineaPig_ EEF2K ( ortholog_one2one ) Macaque_ EEF2K ( ortholog_one2one ) Mouse_ Eef2k ( ortholog_one2one ) Pig_ EEF2K ( ortholog_one2one ) Rat_ Eef2k ( ortholog_one2one ) Rabbit_ EEF2K ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | HSPA12B, HSPA12A, ALPK2, ALPK1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.02(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 5J8H (NMR - ) 5KS5 (NMR - ) 6NX4 (NMR - ) 7SHQ (X-ray 2.34A ) |
| DBSNP | rs9935059 rs17841292 rs147978363 rs4783453 rs56137739 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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