| Gene Information | |
|---|---|
| Gene Name | EDF1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 148 |
| Protein Names | Endothelial differentiation-related factor 1 (EDF-1) (Multiprotein-bridging factor 1) (MBF1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000107223 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O60869 |
| Gene Card | EDF1 |
| Uniprot ID | O60869 |
| Pfam | PF01381; PF08523 |
| In ASD | no |
| Allosteric Prediction | no (-0.894050996) |
| Ortholog in Animals | Alpaca_ EDF1 ( ortholog_one2one ) Dog_ EDF1 ( ortholog_one2one ) GuineaPig_ EDF1 ( ortholog_one2one ) Mouse_ Edf1 ( ortholog_one2one ) Pig_ EDF1 ( ortholog_one2one ) Rat_ Edf1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in brain, liver, lung, kidney and heart (at protein level). Ubiquitously expressed. More abundant in heart, pancreas, liver, intestine and adipose tissues. {ECO:0000269|PubMed:10567391, ECO:0000269|PubMed:12040021, ECO:0000269|PubMed:9813014}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1X57 (NMR - ) 6ZVH (EM 2.90A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm. Nucleus. Note=Also nuclear upon binding to NR5A1 and treatment of cells with TPA or forskolin. |
| Mouse PG classification | NA |
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